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Intervention: Canagliflozin (JNJ-28431754)

Found 59 matching trials

A Study to Assess the Effects of Canagliflozin (JNJ-28431754) on the Pharmacokinetics, Pharmacodynamics, and Safety of Glyburide in Healthy Volunteers

PHASE1

The purpose of this study is to determine how multiple doses of canaglifloz...

Status

Completed

Location

Multiple Locations

Start Date

2008-07

Trial ID

NCT01733108

Treatments Being Tested

Glyburide Canagliflozin (JNJ-28431754)

A Study to Assess the Bioequivalence of Fixed Dose Combination (FDC) Tablets of Canagliflozin and Metformin Immediate Release (IR) With Respect to the Individual Components of Canagliflozin and Metformin IR Tablets in Healthy Volunteers

PHASE1

The purpose of this study is to evaluate the bioequivalence of a fixed dose...

Status

Completed

Location

Multiple Locations

Start Date

2011-09

Trial ID

NCT01463228

Treatments Being Tested

A (canagliflozin and metformin IR individual tablets) / B (canagliflozin/metformin IR FDC tablets)B (canagliflozin/metformin IR FDC tablets / A (canagliflozin and metformin IR individual tablets)

A Study to Assess the Bioequivalence of 2 Fixed Dose Combination (FDC) Tablets of Canagliflozin and Metformin Immediate Release (IR) (50 mg/1,000 mg) With Respect to the Individual Components of Canagliflozin (1 x 100 mg) and Metformin IR Tablets (2 x 1,000 mg) in Healthy Volunteers

PHASE1

The purpose of this study is to evaluate the bioequivalence of fixed dose c...

Status

Completed

Location

Multiple Locations

Start Date

2011-09

Trial ID

NCT01454622

Treatments Being Tested

A (canagliflozin and metformin IR individual tablets) / B (canagliflozin/metformin IR FDC tablets)B (canagliflozin/metformin IR FDC tablets / A (canagliflozin and metformin IR individual tablets)

A Drug Interaction Study of Warfarin and Canagliflozin in Healthy Adult Volunteers

PHASE1

The purpose of the study is to assess the effect of multiple oral doses of ...

Status

Completed

Location

Multiple Locations

Start Date

2010-09

Trial ID

NCT01195324

Treatments Being Tested

Canagliflozin/Warfarin Canagliflozin/Warfarin

A Study to Evaluate the Efficacy and Safety of the Addition of Canagliflozin in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin and Sitagliptin

PHASE4

The purpose of this study is to assess the effect of canagliflozin (JNJ-284...

Status

Completed

Location

Multiple Locations

Start Date

2014-02

Trial ID

NCT02025907

Treatments Being Tested

Canagliflozin, 100 mg Canagliflozin, 300 mg Placebo

The Effect of Food on the Administration of Canagliflozin in Healthy Adult Volunteers

PHASE1

The purpose of this study is to assess the effect of food on the absorption...

Status

Completed

Location

Multiple Locations

Start Date

2011-04

Trial ID

NCT01343290

Treatments Being Tested

Canagliflozin

A Pharmacokinetic Dose Proportionality Study of Canagliflozin in Healthy Volunteers

PHASE1

The purpose of this study is to evaluate the effect of dose on the pharmaco...

Status

Completed

Location

Multiple Locations

Start Date

2011-05

Trial ID

NCT01340677

Treatments Being Tested

Canagliflozin, 50 mg Canagliflozin, 300 mg Canagliflozin, 100 mg

Pharmacokinetics of a Fixed Dose Combination of Canagliflozin/Metformin Coadministered With Food

PHASE1

The purpose of this study is to assess the effect of coadministration of a ...

Status

Completed

Location

Multiple Locations

Start Date

2014-01

Trial ID

NCT02039258

Treatments Being Tested

CANA/MET XR FDC

A Study of 28431754 (Canagliflozin) on Gastrointestinal Glucose Absorption and Metabolism in Healthy Volunteers

PHASE1

The purpose of this study is to evaluate the effect of canagliflozin on gas...

Status

Completed

Location

Multiple Locations

Start Date

2010-11

Trial ID

NCT01173549

Treatments Being Tested

Canagliflozin/Placebo Placebo/Canagliflozin no intervention

A Study to Assess Electrocardiogram Results in Healthy Volunteers Receiving Canagliflozin (JNJ-28431754)

PHASE1

The purpose of this study is to assess the effect of canagliflozin (JNJ-284...

Status

Completed

Location

Multiple Locations

Start Date

2008-06

Trial ID

NCT01787357

Treatments Being Tested

Canagliflozin (JNJ-28431754)Placebo Moxifloxacin

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